2026 March Madness picks: Predictions against the spread, odds for second-round games Saturday

2026 March Madness picks: Predictions against the spread, odds for second-round games Saturday

CBS Sports general

Key Points:

  • The 2026 NCAA Tournament reaches the Round of 32 on Saturday, with 32 teams competing for a spot in the Sweet 16, featuring several top seeds and potential Cinderella stories like No. 11 VCU and No. 12 High Point.
  • Top seeds Duke and Michigan survived tough first-round games and face challenging opponents TCU and Saint Louis respectively, while mid-seed matchups such as Houston vs. Texas A&M and Nebraska vs. Vanderbilt promise intense battles.
  • Expert picks highlight key games: Michigan State vs. Louisville is expected to be high-scoring due to pace of play; Duke is favored to cover the spread against TCU despite potential foul trouble; Texas is a strong underdog pick against Gonzaga

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