2026 March Madness picks: Predictions against the spread, odds for second-round games Saturday
Key Points:
- The 2026 NCAA Tournament reaches the Round of 32 on Saturday, with 32 teams competing for a spot in the Sweet 16, featuring several top seeds and potential Cinderella stories like No. 11 VCU and No. 12 High Point.
- Top seeds Duke and Michigan survived tough first-round games and face challenging opponents TCU and Saint Louis respectively, while mid-seed matchups such as Houston vs. Texas A&M and Nebraska vs. Vanderbilt promise intense battles.
- Expert picks highlight key games: Michigan State vs. Louisville is expected to be high-scoring due to pace of play; Duke is favored to cover the spread against TCU despite potential foul trouble; Texas is a strong underdog pick against Gonzaga