A Different Type of Dementia is Changing What’s Known About Cognitive Decline

A Different Type of Dementia is Changing What’s Known About Cognitive Decline

The New York Times health

Key Points:

  • LATE (Limbic-predominant age-related TDP-43 encephalopathy) is a recently recognized form of dementia that is changing how cognitive decline is understood and diagnosed.
  • New guidelines published this year help doctors identify LATE, which is estimated to affect about one-third of people aged 85 and older and 10% of those 65 and older.
  • LATE can mimic Alzheimer's disease clinically, with similar memory problems, leading to some patients being misdiagnosed with Alzheimer's instead of LATE.
  • Unlike Alzheimer's, LATE typically progresses more slowly and is usually less severe on its own, offering some reassurance to patients and families, but there is currently no specific treatment for it.
  • When L

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