A rare condition killed a 24-year-old first-time NYC Marathon runner. Its warning signs can be easy to miss.

Key Points:

• Rachel Apa, a 24-year-old runner, died from rhabdomyolysis, a rare and potentially fatal condition triggered by excessive exertion, after collapsing near the finish line of the 2026 New York City Marathon.
• Rhabdomyolysis involves rapid breakdown of skeletal muscle, releasing toxic substances that can cause kidney failure and dangerous heart arrhythmias if not treated promptly.
• Risk factors include dehydration, heat exposure, illness, certain genetic conditions, drug use, and intense physical activity, but it can affect anyone regardless of age or fitness level.
• Symptoms often mimic normal exercise pain but may include severe muscle soreness, weakness, confusion, nausea, and dark urine; early recognition and hydration with electrolytes are crucial for prevention and treatment.
• Despite its dangers, experts emphasize that exercise-related rhabdomyolysis is rare and should not discourage participation in marathons or other physical activities, highlighting the importance of gradual training and awareness of symptoms.