Autoimmune field buoyed by successes with CAR-T treatments

Autoimmune field buoyed by successes with CAR-T treatments

statnews.com health

Key Points:

  • Georg Schett, a German physician-scientist, explored using special T cells called chimeric antigen receptors (CARs) to treat a young patient severely ill with lupus.
  • Schett had the capability to produce these CAR T cells at his institution, addressing a significant part of the challenge.
  • A major obstacle was the patient's parents, who were initially fearful and opposed the treatment due to concerns that T cells might trigger or worsen autoimmune disease.
  • The skepticism reflected a broader apprehension at the time about the safety of using T cells in autoimmune conditions.

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