Autoimmune field buoyed by successes with CAR-T treatments
Key Points:
- Georg Schett, a German physician-scientist, explored using special T cells called chimeric antigen receptors (CARs) to treat a young patient severely ill with lupus.
- Schett had the capability to produce these CAR T cells at his institution, addressing a significant part of the challenge.
- A major obstacle was the patient's parents, who were initially fearful and opposed the treatment due to concerns that T cells might trigger or worsen autoimmune disease.
- The skepticism reflected a broader apprehension at the time about the safety of using T cells in autoimmune conditions.