Cannabis Compounds Do Something Surprising to Your Liver, Study Finds

Cannabis Compounds Do Something Surprising to Your Liver, Study Finds

VICE health

Key Points:

  • A new study from Hebrew University of Jerusalem found that non-psychoactive cannabis compounds CBD and CBG improved liver function and metabolic health in obese mice with metabolic dysfunction-associated steatotic liver disease (MASLD).
  • MASLD, the most common chronic liver disorder worldwide, affects about one-third of adults and currently has very few drug treatments available.
  • The compounds appeared to work by enhancing hepatic energy reserves and lysosomal function, helping liver cells clear harmful fats and waste more effectively, even in mice on a high-fat diet.
  • CBG showed particularly strong effects on reducing body fat, improving insulin sensitivity, and lowering cholesterol levels compared to CBD.
  • While promising, the findings are limited to mouse models with daily abdominal injections

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