College football odds, lines, schedule, picks: Week 1 predictions, best bets today
CBS Sports • • sports
Key Points:
- The 2026 college football Week 1 schedule features 90 FBS games, highlighted by Lane Kiffin’s LSU debut against Clemson, with LSU favored by 10.5 points, and a ranked matchup between No. 9 Ole Miss and No. 24 Louisville on Sunday.
- Ohio State, ranked No. 1, opens its season heavily favored (-50.5) against Ball State, while notable non-conference games include UCLA vs. Cal and Baylor vs. Auburn.
- SportsLine’s advanced model, which simulates every FBS game 10,000 times and has a strong track record on money-line picks, recommends Auburn (-7.5) over Baylor and Cincinnati (-7.5) over Boston College as confident Week 1 bets.
- The model factors in transfer portal impacts and projects Auburn’s QB Byrum Brown to have a standout performance, while Cincinnati benefits from Boston College’s recent poor road record and overall struggles.
- Full Week 1 game picks, odds, and predictions are available via SportsLine, which also highlights a potential Big Ten upset and provides detailed betting insights for all matchups.
