College football odds, schedule, picks: Week 0 predictions, best bets today
Key Points:
- Week 0 of the 2026 college football season features eight FBS games on Saturday, Aug. 29, starting in Ireland with UNC vs. TCU and ending in Las Vegas, with No. 14 USC and Florida State as heavy favorites in two matchups.
- UNC vs. TCU kicks off the season in Dublin, Ireland, while North Dakota State makes its FBS debut hosting Jacksonville State, with most games having single-digit point spreads.
- SportsLine’s advanced model, upgraded for the 2026 season to include transfer portal data, provides picks for every Week 0 game and is currently on a 31-19 run on top-rated money-line bets since 2024.
- Top model picks include Virginia (-4) to cover against NC State, benefiting from NC State’s poor road underdog record, and New Mexico State (+31.5) to cover against Florida State, which struggled in late 2025 and added a new quarterback with a challenging past performance.
- Bettors are encouraged to check SportsLine for full Week 0 predictions and betting insights, including potential upsets and spread covers, based on extensive simulations of each game.