College football picks: Predictions, odds for key top 25 games in Week 6

College football picks: Predictions, odds for key top 25 games in Week 6

CBS Sports • • sports

Key Points:

  • The highly anticipated matchup between No. 2 Georgia and No. 6 Alabama in Tuscaloosa features two undefeated teams with strong College Football Playoff prospects, highlighting Alabama's explosive offense against Georgia's top-10 rushing and scoring defense.
  • Before that game, No. 21 UCLA faces No. 13 Oregon, with Oregon expected to miss quarterback Dante Moore; a loss for Oregon could severely damage their CFP chances, while UCLA aims to continue their strong season under coach Bob Chesney.
  • Other notable Big Ten and top-25 matchups include No. 7 Indiana at Nebraska, No. 1 Texas vs. Oklahoma, No. 9 Ole Miss at Vanderbilt, No. 10 LSU at Kentucky, No. 14 Missouri at Texas A&M, and No. 19 USC at Penn State, with several games posing upset risks.
  • Expert predictions favor Texas over Oklahoma by 8.5 points, Oregon over UCLA by 11.5 points, LSU over Kentucky by 10.5 points, and a close game between Alabama and Georgia, with a slight edge to Georgia (+1.5), especially given potential weather impacts.

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