Forever Chemicals Linked to Faster Aging in Middle-Aged Men, Study Finds

Forever Chemicals Linked to Faster Aging in Middle-Aged Men, Study Finds

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Key Points:

  • A new study led by Shanghai Jiao Tong University links exposure to two PFAS chemicals, PFNA and PFOSA, with accelerated biological aging in middle-aged men, based on epigenetic clock analysis of blood samples from a US health survey.
  • PFAS, known as "forever chemicals," are synthetic substances widely used since the mid-20th century for their durability and resistance, but they persist in the environment for up to a thousand years and are increasingly associated with adverse health effects.
  • The study found PFNA and PFOSA in 95% of participants' blood, with higher PFNA levels strongly predicting faster epigenetic aging in men aged 50-64, while no similar effect was observed in women, possibly due to

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