Glyphosate: A common weedkiller may induce anxiety by disrupting gut bacteria

Glyphosate: A common weedkiller may induce anxiety by disrupting gut bacteria

PsyPost health

Key Points:

  • A new study published in Frontiers in Toxicology found that chronic exposure to glyphosate at government-approved safe levels caused heightened anxiety and altered gut microbiomes in rats, leading to hypervigilance and misinterpretation of harmless stimuli as threats.
  • Rats exposed to glyphosate showed increased activity in the bed nucleus of the stria terminalis, a brain region linked to anxiety, without significant changes in other fear-processing areas like the amygdala or prefrontal cortex.
  • The herbicide disrupted gut bacteria, notably reducing Lactobacillus populations essential for serotonin production, which likely contributed to the observed anxiety and altered emotional responses.
  • The study only tested male rats and measured gut bacteria at the experiment's end, indicating a need for further research including female subjects and more frequent microbiome analysis to fully understand the timing and sex-specific effects.
  • These findings challenge current regulatory safety thresholds for glyphosate, suggesting that its impact on gut bacteria and brain health warrants a reevaluation of acceptable exposure limits.

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