Groundbreaking study shows Alzheimer's may be reversible in advanced stages
WKYC • • health
Key Points:
- Researchers from University Hospitals, Case Western Reserve University, and the Cleveland VA have successfully reversed advanced Alzheimer's in mice by restoring the brain's energy balance, challenging the long-held belief that the disease is irreversible.
- The study, published in Cell Reports Medicine, focuses on stabilizing NAD+ levels in the brain using a compound called P7C3-A20, which halted disease progression and fully restored cognitive function in mouse models without relying on amyloid-targeting therapies.
- Unlike over-the-counter NAD+ supplements, P7C3-A20 maintains NAD+ homeostasis at normal physiological levels, potentially offering a safer approach to supporting brain energy and function.
- The research team has formed Glengary Brain Health to advance the treatment toward human trials, aiming
