Mpox vaccination urged after more-severe strain detected in San Francisco

Key Points:

• California health officials have identified a potentially more severe strain of mpox, Clade I, in San Francisco, marking the seventh such case in the state, with the infected individual requiring hospitalization.
• Clade I is considered more concerning than the more common Clade II strain due to its potential for causing severe illness and easier transmission through close personal contact.
• Mpox cases caused by Clade II are increasing in California, with current weekly rates significantly higher than in previous years, primarily affecting unvaccinated individuals.
• Health officials strongly recommend vaccination for high-risk groups, including men who have sex with men, transgender and nonbinary individuals, people with HIV, and those traveling to areas with Clade I outbreaks.
• Symptoms of mpox include rash, sores, fever, and swollen lymph nodes; individuals with symptoms should seek medical testing promptly, and those exposed should get vaccinated and avoid contact until fully recovered.