Multiple Sclerosis May Have Two Distinct Subtypes, Scientists Discover
ScienceAlert • • health
Key Points:
- A new study by University College London scientists suggests there may be two distinct subtypes of multiple sclerosis (MS), identified through machine learning analysis of blood tests and brain scans from 634 patients.
- The study found an "early-sNfL" subtype characterized by early elevated serum neurofilament light chain (sNfL) levels and faster brain lesion development, and a "late-sNfL" subtype with slower progression and later rises in sNfL.
- Combining sNfL protein levels with MRI data allowed the AI model to reveal biological patterns of MS beyond traditional symptom-based classification, potentially enabling more personalized treatment approaches.
- The research highlights the value of integrating blood biomarkers with imaging to improve understanding of
