NFL Monday Night Football preview: Vikings defense gets a tough test vs. Josh Allen and Bills

Key Points:

• The Minnesota Vikings, boasting the NFL's best defense by EPA per play, will face the Buffalo Bills and quarterback Josh Allen, who leads all QBs in EPA per play, in a Monday night matchup between two 6-1 teams.
• The Vikings' offense, led by Carson Wentz due to Kyler Murray's hamstring injury, struggles significantly, ranking near the bottom in points and yards per game, but may find opportunities against a Bills defense that has allowed the third-most passing yards this season.
• Vikings wide receiver Justin Jefferson, frustrated by poor quarterback play and recent performance, could be revitalized by Wentz's experience, especially against a Bills defense that has conceded substantial yardage and touchdowns to receivers.
• Betting markets favor the Bills as slight favorites despite the Vikings' strong defense, with Minnesota hoping Wentz can spark their offense and capitalize on home-field advantage for the first time as underdogs this season.
• Fantasy themes to watch include Wentz's impact on the Vikings passing game, Buffalo receiver DJ Moore's challenge against a tough Minnesota secondary, and how the Vikings manage their running back situation amid recent inefficiencies and speculation about roster changes.