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Researchers looking into whether GLP-1 drugs can help slow aging
abcnews.com • • health
Key Points:
- Researchers at the University of Texas Medical Branch are conducting one of the first clinical trials to investigate whether tirzepatide, the active ingredient in Zepbound, can slow biological aging by 10 to 15%.
- The UTMB trial will monitor adults aged 55 to 70 who qualify for weight loss treatment, assessing biological age markers, inflammation, cognitive function, strength, and mobility.
- Previous studies, including one by UC San Diego and Case Western Reserve University, found that semaglutide (Ozempic, Wegovy) showed changes in DNA-based aging clocks suggesting slower aging in adults with HIV and abnormal fat buildup.
- Despite promising early results, there is currently no scientific evidence supporting the use of GLP-1 medications for longevity in healthy individuals, and further rigorous clinical trials are needed.
