Review finds modest relief, major risks from a go-to pain drug

Review finds modest relief, major risks from a go-to pain drug

Earth.com health

Key Points:

  • Tramadol, widely prescribed for chronic pain due to its perceived balance of effectiveness and safety, has been re-evaluated in a large review analyzing 19 clinical trials with 6,506 participants.
  • The review found that tramadol provides only slight pain relief that is unlikely to improve daily functioning, while significantly increasing the risk of serious side effects, particularly heart-related problems.
  • Common side effects such as nausea, dizziness, constipation, and sleepiness were also more frequent among tramadol users, which can negatively impact quality of life, especially in older adults.
  • The study highlights concerns about tramadol’s safety, noting that its potential harms likely outweigh its limited benefits, and calls for minimizing its use amid the broader opioid crisis.
  • These findings suggest a need to reconsider tramadol’s role in chronic pain management, emphasizing caution due to the drug’s risks despite its widespread use and trust among patients and doctors.

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