Scientists Found a Protein That Could Keep Your Brain From Growing Old
Key Points:
- Researchers from the National University of Singapore discovered that the protein DMTF1, which regulates gene expression, is repressed in aged neural stem cells, contributing to the decline in brain cell regeneration with age.
- Experiments showed that restoring DMTF1 expression in aged neural stem cells helped revive their ability to proliferate, even without reversing telomere shortening, a key marker of cellular aging.
- The study suggests that targeting DMTF1 could lead to therapies that promote neural stem cell regeneration and potentially mitigate age-related cognitive decline.
- While the research was conducted in cell systems and mouse models, it provides a foundational understanding of molecular changes in brain aging and opens avenues for future therapeutic development.
- Scientists emphasize that such