Silver diamine fluoride treatment could halt cavities without shots, drilling or sedation

Key Points:

• A University of Michigan-led clinical trial demonstrated that silver diamine fluoride (SDF), a simple and inexpensive liquid, effectively arrests tooth decay in young children without the need for drilling, shots, or sedation.
• The Phase III trial involving 830 children under 6 showed that 38% SDF arrested decay in more than half of affected baby teeth when applied at six-month intervals.
• SDF has been used off-label in the U.S. since 2014 but lacked large clinical trial data for FDA approval; this new evidence supports its safety and efficacy, potentially leading to broader FDA approval.
• The main drawback of SDF is cosmetic, as it permanently darkens decayed areas of teeth, but its ease of use makes it especially valuable for young children, older adults, and those with dental anxiety or disabilities.
• Researchers and dental experts believe FDA approval could increase use by providers, improve insurance coverage, and provide a non-invasive treatment option that prevents pain, infection, and the need for surgery in many patients.