Some people are taking Cialis for more than sex : NPR
Key Points:
- Tadalafil (Cialis), commonly prescribed for erectile dysfunction, is increasingly promoted in biohacking and wellness circles as a potential longevity drug with benefits for cardiovascular health, brain function, and athletic performance, despite not being approved for these uses.
- Observational studies suggest men taking tadalafil have lower rates of cardiovascular disease, mortality, and dementia, but these findings show associations rather than causation, and randomized controlled trials are lacking.
- Experts like Dr. Robert Kloner acknowledge the promising signals from research but caution that more rigorous studies are needed; pharmaceutical companies have little incentive to fund such trials due to the drug's generic status.
- Online clinics market low-dose tadalafil for longevity to both men and women over 40, though some cardiologists express concern over off-label use without stronger human data on safety and efficacy.
- The Princeton Consensus Panel recently deemed low-dose tadalafil "appropriate" for certain men at elevated cardiovascular risk, reflecting growing but cautious acceptance of its preventive potential within the medical community.