
Something Grim Is Happening to People Who Go Off GLP-1s
Key Points:
- Many people who lose weight using Ozempic and other GLP-1 agonists struggle to stop the medication because their hunger returns strongly, often leading to weight regain and suggesting potential lifelong dependency.
- Research shows that patients who discontinue these drugs typically regain about two-thirds of the weight they lost, with some physicians observing 60 to 80 percent weight regain among their patients.
- Celebrities like Oprah Winfrey have publicly stated they plan to remain on these medications indefinitely, likening the need to continue treatment to managing chronic conditions such as high blood pressure.
- Experts recommend developing an "exit strategy" that includes adopting healthier lifestyle habits, such as improved diet and exercise, while on the medication to help sustain weight loss after stopping the












