Study: Pacific Islanders Appear To Have Most Ancient Human DNA On Earth

Study: Pacific Islanders Appear To Have Most Ancient Human DNA On Earth

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Key Points:

  • People in Near Oceania, including New Guinea and surrounding islands, carry more ancient Denisovan-like DNA than any other population, inherited from three distinct archaic human groups over tens of thousands of years.
  • The Sepik Islanders of New Guinea have 25 times more Denisovan DNA than East Asians, and overall, Oceanic genomes contain about 2.5 times more ancient inherited sequences than European genomes.
  • Genetic analysis revealed that long-term isolation and population bottlenecks shaped unique genetic profiles in Near Oceanic groups, leading to distinct evolutionary paths influenced by random genetic drift.
  • Some Denisovan-derived genetic variants remain active today, especially in immune-related genes like TRPS1, JAK1, GBP2, and OAS1, suggesting these ancient genes have been favored by natural selection and may affect immune responses.
  • This research highlights Near Oceania as a critical region for understanding human evolution, showing that archaic human DNA continues to influence modern populations and their adaptation to local environments.

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