Texas study suggests nasal spray could reverse brain aging
Dallas News • • health
Key Points:
- Texas A&M researchers developed a nasal spray containing extracellular vesicles from neural stem cells that reduced brain inflammation and improved memory and cognitive function in aged mice, with effects lasting months after just two doses.
- The treatment targets "neuroinflammaging," a chronic brain inflammation linked to age-related cognitive decline, by delivering microRNAs that regulate gene activity and enhance cellular energy in the brain.
- Current treatments for age-related brain diseases like dementia and Alzheimer's are limited, partly due to the brain's protective barrier, but this nasal spray bypasses that barrier non-invasively.
- While promising, the research is preliminary, and further studies are needed to verify safety, dosing, and effectiveness in humans before clinical application.
- The researchers are pursuing patent protection and aim to develop the therapy for future human trials, with potential to replace invasive or long-term medication-based treatments.
