AI Generated Image
The hunt for a natural molecule that can release cellular energy
Phys.org • • technology
Key Points:
- Researchers at The Ohio State University have identified the first noncoding RNA derived from human cells that can bind to ATP, challenging the belief that only proteins handle ATP activity in the body.
- This noncoding RNA, featuring a compact and stable G-quadruplex structure, may function similarly to ATPase enzymes that catalyze ATP decomposition, potentially enabling new therapeutic applications.
- The discovery builds on prior research identifying viral RNAs capable of ATP binding and suggests that RNA molecules could be engineered as therapeutic nanoparticles targeting diseases like cancer.
- The team is currently investigating the exact mechanism of ATP binding by this RNA and its possible role as part of an ATPase motor complex, which could revolutionize drug discovery and nanomedicine.
