These 80-year-olds have the memory of 50-year-olds. Scientists now know why
Science Daily • • general
Key Points:
- SuperAgers are older adults who perform on memory tests at levels comparable to people at least 30 years younger, challenging the belief that cognitive decline is inevitable with age.
- Research has identified two mechanisms behind SuperAging: resistance to developing Alzheimer's-related plaques and tangles, and resilience where these proteins do not impair brain function.
- SuperAgers exhibit youthful brain structures, including thicker anterior cingulate cortex regions and unique cellular features like more von economo neurons, which support memory and social behavior.
- Strong social connections and outgoing personalities are common among SuperAgers, though their exercise and lifestyle habits vary.
- The Northwestern SuperAging Program, ongoing for over 25 years, relies on annual evaluations and brain donations to uncover insights that may inform future interventions to preserve cognitive health and reduce dementia risk.
