This surprising drug may soon be used to treat panic disorder

This surprising drug may soon be used to treat panic disorder

New York Post health

Key Points:

  • A Brazilian study found that low doses of minocycline, a common antibiotic with anti-inflammatory properties, may help reduce symptoms of panic disorder by targeting brain inflammation.
  • In animal tests, minocycline reduced panic-like behaviors and decreased activity in the brain region associated with panic responses, the locus coeruleus.
  • A small human trial showed minocycline lowered pro-inflammatory markers and improved anxiety symptoms in panic disorder patients, suggesting a different mechanism than traditional benzodiazepines.
  • Unlike benzodiazepines, which carry risks of addiction and serious side effects, minocycline is generally safe and was used at lower doses that may minimize side effects and antibiotic resistance concerns.
  • Researchers emphasize the need for larger clinical trials before minocycline can be prescribed for panic disorder, but the findings offer promising potential for new inflammation-targeting treatments.

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