'Universal' nasal-spray vaccine protects against viruses, bacteria and allergens in mice
Live Science • • general
Key Points:
- A new experimental nasal-spray vaccine tested in mice could potentially provide broad protection against various bacteria, allergens, and respiratory viruses by activating both innate and adaptive immune systems.
- Unlike conventional vaccines targeting specific antigens, this vaccine mimics signals that keep innate immune cells in the lungs active for months, offering a first-line defense against diverse pathogens.
- In mouse studies, the vaccine protected against SARS-CoV-2, other coronaviruses, bacteria like Staphylococcus aureus and Acinetobacter baumannii, and allergens from house dust mites for at least three months.
- Experts highlight the vaccine's potential to revolutionize protection against common respiratory infections, but emphasize that human trials are needed to confirm safety and effectiveness.
