Your guide to fall vaccines. What's new with flu, COVID-19 and RSV

Key Points:

• A coalition of medical societies and the Vaccine Integrity Project launched Spreadthefacts.org as a centralized, science-based resource for COVID-19, flu, and RSV vaccine information to address public confusion amid shifting federal guidelines.
• New vaccines for the 2026-27 season include mFLUSIVA, an mRNA flu shot authorized for ages 50+, and updated COVID-19 vaccines targeting the XFG variant, with recommendations emphasizing annual vaccination for most adults and vulnerable groups.
• Scientific data show flu vaccines reduce hospitalization risk by 31% in seniors and flu-related death risk by 80% in children; COVID-19 vaccines significantly lower hospitalization and death rates, especially in older adults and immunocompromised individuals.
• RSV vaccines are recommended as a one-time dose for high-risk groups, including adults 50+, seniors 75+, pregnant women, and infants without maternal protection, with monoclonal antibodies advised for young infants entering their first RSV season.
• Updated vaccines are becoming widely available at pharmacies, clinics, and physician offices nationwide, with clear guidance urging timely vaccination to maximize protection during peak respiratory virus seasons.