Amid social media challenge, calls to poison centers for Benadryl among teens more than double this year than last

Amid social media challenge, calls to poison centers for Benadryl among teens more than double this year than last

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Key Points:

  • Calls to poison centers involving diphenhydramine and teens in early 2026 have more than doubled compared to the same period in 2025, indicating a rising trend in misuse of the medication.
  • The increase is largely attributed to teens intentionally abusing diphenhydramine to achieve a euphoric high, rather than accidental ingestion, with intentional abuse cases rising from 7.3% in 2020 to 13.2% in 2026.
  • Connecticut officials reported three recent teen deaths linked to diphenhydramine overdoses, though it remains unclear if these are connected to social media challenges promoting misuse.
  • Diphenhydramine overdose can cause serious health risks including hallucinations, seizures, heart problems, and loss of consciousness, prompting warnings from America's Poison Centers and the medication's manufacturer.
  • Kenvue, maker of Benadryl, condemned the social media trend encouraging diphenhydramine misuse and emphasized the importance of product safety and stopping dangerous behaviors immediately.

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