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Cannabis Combo Eases Agitation From Dementia
Newser • • health
Key Points:
- A small Phase 2 trial involving 120 advanced dementia patients found that nearly 90% of those given a custom THC/CBD oil showed reduced agitation after 12 weeks, compared to less than 25% on placebo.
- The oil contained low-dose THC (2mg) and high-dose CBD (100mg) per milliliter, was taken twice daily, and did not cause significant psychoactive effects or major safety issues beyond those typical in very ill patients.
- Experts caution that the findings are preliminary and the formulation is not FDA-approved, emphasizing that cannabinoid treatments should be prescribed and monitored by medical professionals rather than using over-the-counter products.
- The study's results are considered promising given the current reliance on antipsychotics and opioids for agitation, which can have serious side effects, and previous research has linked CBD to reduced inflammation in Alzheimer's disease.
