College football odds, picks: Week 0 predictions, best bets today
Key Points:
- Week 0 of the 2026 college football season kicks off on Saturday, Aug. 29, featuring eight FBS games starting in Ireland and ending in Las Vegas, with No. 14 USC and Florida State as heavy favorites in two matchups.
- UNC vs. TCU (-9.5) in Dublin opens the season, and North Dakota State makes its FBS debut as a 7-point favorite hosting Jacksonville State, highlighting key early-season matchups.
- SportsLine’s advanced model, upgraded for 2026 to factor in the transfer portal, has a strong 31-19 record on top-rated money-line picks since 2024 and provides detailed predictions for all Week 0 games.
- Notable model picks include Virginia (-4.5) to cover against NC State and New Mexico State (+32.5) to cover at Florida State, citing factors like team trends, player performance, and historical ATS records.
- Fans and bettors are encouraged to visit SportsLine for comprehensive Week 0 picks, including spreads, money lines, and totals, based on simulations of each FBS game 10,000 times.