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Faster Alzheimer's decline linked to common pill taken by millions
walesonline.co.uk • • health
Key Points:
- New research from the University of Florida suggests that glucosamine, a common over-the-counter supplement for joint health, may be linked to faster progression of Alzheimer's disease and increased dementia risk in people with mild cognitive impairment (MCI).
- The study found that individuals with MCI who took glucosamine had a 25% higher chance of developing dementia, and those already diagnosed with dementia had a 25% increased risk of death associated with glucosamine use.
- Researchers identified a potential mechanism involving excessive sugar-tagging of brain proteins, which glucosamine may exacerbate, contributing to Alzheimer's progression as shown in mouse models and human brain tissue analysis.
- While the findings raise concerns, they do not prove causation, and experts urge individuals currently taking glucosamine to consult their GP before making any changes to their supplement regimen.
- The study highlights the need for further investigation into glucosamine’s effects on brain health, especially in older adults with memory issues, while those without cognitive symptoms may be advised to continue use under medical guidance.
