Immune cells leave ‘memory’ of obesity after weight loss
Yahoo • • health
Key Points:
- A University of Birmingham study indicates that obesity may create a lasting "memory" in the immune system, persisting even after significant weight loss.
- Researchers analyzed blood and fat tissue samples from various groups, including individuals with obesity, those with Alström syndrome, participants in exercise interventions, and patients undergoing joint replacement surgery.
- The study found that short-term weight loss might not immediately reduce the risk of obesity-related diseases such as Type 2 diabetes and certain cancers.
- Reversing the immune system's "obesity memory" likely requires sustained weight management over a period of five to ten years following major weight loss.
- Additional research included studying immune cells from mice on high-fat diets and healthy human volunteers to better understand obesity-related immune dysregulation.
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