Male sex hormone loss aids brain tumour growth
Nature • • health
Key Points:
- Men generally experience higher cancer incidence and worse outcomes than women, potentially due to the influence of androgens, male sex hormones.
- Androgens are known to suppress the immune system's ability to fight cancer, and blocking their signaling can improve immunotherapy effectiveness in several tumor types.
- Contrary to this trend, new research by Lee et al. published in Nature reveals that androgens may actually inhibit the growth of brain tumors.
- This finding suggests a complex and tissue-specific role of androgens in cancer progression, highlighting the need for further investigation into sex hormone effects on different cancers.
