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NFL Week 2 odds, predictions: Picks, best bets from 10,000 computer simulations
CBS Sports • • general
Key Points:
- The Rams and 49ers, who played in Australia last week, both have home games in Week 2, with the 49ers favored by 12.5 points against Miami and the Rams favored by 7 points against the Giants.
- Six Week 2 NFL games feature spreads of at least a touchdown, influenced by results from Week 1, with updated odds available alongside expert betting advice from SportsLine’s advanced computer model.
- SportsLine’s model, which simulates each game 10,000 times, has a strong track record with over $7,000 in profits for $100 bettors since 2024 and is currently on a 53-39 run on top-rated picks entering Week 2.
- Key Week 2 picks include the Seahawks favored to cover (-3.5) against the Cardinals and the Buccaneers favored to cover (-8.5) versus the Browns, with both teams showing statistical advantages based on recent performance and simulations.
- For comprehensive Week 2 NFL picks, including an underdog predicted to win outright by a touchdown, bettors are encouraged to visit SportsLine for detailed predictions and betting strategies.
