NFL Week 4 picks, predictions: ATS, over/under expert bets for Sunday’s schedule

Key Points:

• Five NFL teams remain undefeated at 3-0 entering Week 4, while five teams are still seeking their first win, setting up intriguing matchups such as Minnesota vs. Miami and Kansas City vs. Las Vegas.
• In the London game, the Colts are favored over the Commanders despite the Colts' struggling defense, with trends showing low-scoring games in London and the Commanders' games often hitting the over without QB Jayden Daniels.
• Key matchups include the Bills favored over the Patriots despite Buffalo's poor spread record against New England, and the Jaguars, with the NFL's best scoring defense, predicted to edge the Bengals.
• The Raiders aim for their first 4-0 start since 2002 against the Chiefs, while the 49ers are favored over the Broncos if key players return, highlighting significant injury impacts on predictions.
• Several teams show notable statistical trends: the Packers have the NFL's lowest rushing yards and poor pass blocking; the Chargers struggle offensively despite forcing turnovers; and the Panthers' QB Bryce Young leads the league in passing yards, influencing their matchup against the Lions.