Scientists analysed the DNA of world’s oldest land animal. What they found was staggering

Key Points:

• Jonathan, an Aldabra giant tortoise estimated to be 194 years old, is the oldest land animal alive today, and scientists have analyzed his genes to uncover secrets to his exceptional longevity.
• The study, published in Science Advances, identified 287 unique gene variants in Jonathan that help reduce aging effects by regulating inflammation, insulin, DNA repair, and cancer suppression.
• Researchers found that Jonathan’s epigenome, which controls gene activity, remained remarkably stable compared to younger tortoises, particularly in genes related to DNA repair and metabolism, suggesting a mechanism for his extended lifespan.
• This research is the first to investigate the epigenome of a giant tortoise and may provide insights into aging processes that could inform treatments for chronic diseases in humans.
• Jonathan has lived most of his life on Saint Helena island after being brought from the Seychelles 144 years ago, and his species is known for their large size and longevity, often living over 150 years.