Scratching an itch worsens eczema and skin inflammation, study finds
Key Points:
- Scratching a bug bite or rash provides only temporary relief but worsens inflammation and prolongs itching, as shown in a study by University of Pittsburgh researchers using mice models of allergic-contact dermatitis.
- Scratching activates mast cells, which release histamine and other chemicals that increase inflammation and itch, creating a self-perpetuating itch-scratch cycle.
- Mice prevented from scratching or lacking itch-sensing neurons experienced less inflammation, indicating scratching exacerbates skin irritation.
- Despite the harmful effects, scratching may have evolved as a defense mechanism because it activates mast cells that help reduce harmful skin bacteria like Staphylococcus aureus.
- For relief, the American Academy of Dermatology recommends cold compresses and 1% hydrocortisone cream, while cautioning against chronic scratching due to its damaging effects on the skin.