
The clock starts ticking the day you quit your GLP‑1 medication
Key Points:
- A study from Oxford’s Nuffield Department of Primary Care Health Sciences found that discontinuing GLP-1 medications often leads to patients regaining all lost weight within 18 to 24 months, with weight returning faster than after behavioral weight loss programs.
- Cardiometabolic markers such as blood pressure and cholesterol also revert to baseline levels about 16 months after stopping GLP-1 treatment, indicating the need for long-term medication use to maintain benefits.
- Researchers emphasize that obesity is a chronic, relapsing condition, and weight loss through medication alone may not develop the behavioral skills necessary for sustained weight management.
- GLP-1 drugs, originally developed for diabetes, have been approved for obesity treatment but are costly, often









