UConn vs. Duke odds, prediction: 2026 NCAA Tournament picks from proven model

UConn vs. Duke odds, prediction: 2026 NCAA Tournament picks from proven model

SportsLine sports

Key Points:

  • The top-seeded Duke Blue Devils face the second-seeded UConn Huskies in the NCAA Tournament East Region Elite 8 for a Final Four spot, with the game scheduled for Sunday at 5:05 p.m. ET in Washington, D.C.
  • UConn (32-5) seeks its eighth Final Four appearance and seventh NCAA championship, while Duke (35-2) aims for its 19th Final Four and sixth NCAA title; Duke leads the all-time series 6-4 and is favored by 5.5 points.
  • Betting odds show Duke at -240 on the money line and UConn at +196, with the over/under for total points set at 134.5, up from an opening of 132.
  • The SportsLine Projection Model, which has a strong track record on college basketball picks, simulated the game 10,000 times, predicting the total score will go over and that one side of the spread will hit nearly 60% of the time.
  • Fans and bettors are encouraged to consult the SportsLine model for detailed predictions and the best betting strategy for the Duke vs. UConn matchup.

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