Week 3 NFL score predictions by proven computer model

Key Points:

• The third week of the 2026 NFL season features 14 Sunday matchups, with notable spreads including Texans vs. Colts (+2.5), Bengals vs. Steelers (+3.5), Chargers vs. Bills (-7), and Rams vs. Broncos (+2.5) on Sunday Night Football.
• The highest total points line on Sunday is 52.5 for Ravens vs. Cowboys in Brazil, while the lowest is 39.5 for Titans vs. Giants, which dropped after Jaxson Dart's injury.
• SportsLine’s proven model, which simulates each NFL game 10,000 times, has a strong track record with over $7,000 profit for $100 bettors and a 53-41 run on top-rated picks since 2024.
• For Week 3, the model predicts the Rams to narrowly beat the Broncos 22-21, with the Broncos favored against the spread 54% of the time and the over 45.5 points clearing 60% of the time, despite the Rams’ injury challenges.
• The model has locked in exact score predictions for all Week 3 games, including an anticipated upset by an underdog, with full details available exclusively at SportsLine.