Alzheimer’s prevention breakthrough found in decades-old seizure drug

Alzheimer’s prevention breakthrough found in decades-old seizure drug

Fox News health

Key Points:

  • A study by Northwestern University suggests that the anti-seizure drug levetiracetam may prevent the formation of toxic amyloid beta peptides linked to Alzheimer’s disease, potentially offering a new preventive approach.
  • Levetiracetam was shown to inhibit amyloid-beta 42 production in animal models, cultured human neurons, and post-mortem brain tissue from individuals with Down syndrome, who are at high risk for Alzheimer’s.
  • The drug would need to be administered very early—up to 20 years before amyloid-beta 42 levels rise—to be effective, as it cannot reverse damage once dementia has developed.
  • Analysis of prior clinical data indicated that Alzheimer’s patients taking levetiracetam experienced a modest delay in cognitive decline progression compared to

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