College football odds, picks, lines: Week 0 predictions, best bets today
Key Points:
- Week 0 of the 2026 college football season features eight FBS games on Saturday, Aug. 29, starting in Dublin, Ireland, and ending in Las Vegas, with No. 14 USC and Florida State as heavy favorites in their matchups.
- UNC vs. TCU (-7.5) in Dublin kicks off the season, and FCS powerhouse North Dakota State makes its FBS debut hosting Jacksonville State as a 6.5-point favorite.
- A proven SportsLine model, which simulates each game 10,000 times and is on a 31-19 run since 2024, predicts Virginia (-5.5) will cover against NC State, citing NC State’s poor road and season opener performance against the spread.
- The model also suggests New Mexico State (+31.5) will cover against Florida State, highlighting FSU’s recent struggles and quarterback challenges, with the Aggies covering nearly 70% of simulations.
- Full Week 0 college football picks, odds, and predictions are available exclusively on SportsLine, where the model provides insights on winners, spreads, and potential upsets.