Commanders at 49ers 'Monday Night Football' betting odds, picks and predictions: Best bets, player props

Key Points:

• The Washington Commanders are coming off a high-profile overtime blunder against the Giants, impacting public perception and betting markets ahead of their Monday Night Football game against the undefeated San Francisco 49ers.
• The 49ers are favored by 7.5 points, with sportsbooks seeing about 80% of bets on them; however, the Commanders show value as underdogs due to their fluctuating quarterback situation and a point spread projection of -6.
• Key player prop bets include Jayden Daniels to exceed 37.5 rushing yards, given his recent strong running performances, and Stefon Diggs' longest reception to be under 17.5 yards, factoring in his hamstring injury and the 49ers' strong defense.
• Offensive players to watch for touchdowns include Austin Ekeler and Treylon Burks for the Commanders, and George Kittle for the 49ers, with Kittle coming off a three-game touchdown streak and the Commanders vulnerable to tight end scores.
• The 49ers may rely on rookie running back Kaelon Black to fill the void left by Deebo Samuel's absence, potentially increasing his red-zone opportunities against the Commanders' defense.