Common sugar identified as surprise cancer driver
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Common sugar identified as surprise cancer driver

The Independent health

Key Points:

  • A new study from the Wistar Institute reveals that fructose acts as a signaling molecule released by chemotherapy-surviving tumor cells, promoting the spread of ovarian cancer after treatment.
  • Researchers found that fructose suppresses cholesterol in neighboring cells, reducing cell adhesion and enabling cancer cells to escape and metastasize more easily.
  • High dietary fructose intake, such as from sugary drinks, may similarly encourage cancer spread, suggesting that dietary changes could influence cancer progression.
  • The study raises concerns about potential interactions between cholesterol-lowering statins and chemotherapy, especially since many ovarian cancer patients are postmenopausal women who often take statins.
  • Scientists plan further research to determine if these findings apply to other cancer types and to explore the clinical implications of fructose reduction and statin use during cancer treatment.

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