Creatine May Do More Than Boost Muscle Performance
Key Points:
- UCLA researchers discovered that creatine, commonly used for muscle performance, also energizes dendritic immune cells that target tumors in mice and lab-grown human cells.
- The study showed that blocking creatine transport in dendritic cells impaired their survival and ability to activate cancer-killing T-cells.
- Daily creatine injections slowed melanoma growth in mice and enhanced the number and activity of tumor-infiltrating dendritic cells.
- Lab tests indicated creatine improved human dendritic cells' capacity to activate T-cells, suggesting potential for enhancing dendritic cell-based cancer vaccines.
- Researchers emphasize this is preliminary research, and clinical trials are necessary before recommending creatine supplementation for cancer patients.