Full Recovery from Alzheimer’s? Scientists Just Made It Happen in Mice
Indian Defence Review••health
Key Points:
- Researchers at University Hospitals Cleveland Medical Center and collaborators used the compound P7C3-A20 to restore NAD+ levels in mouse models of Alzheimer's, resulting in significant structural and functional brain recovery even at advanced disease stages.
- The study demonstrated that cognitive decline in Alzheimer's may stem from metabolic imbalance rather than irreversible neuron loss, as restoring NAD+ normalized memory, behavior, and cellular damage in affected mice.
- P7C3-A20 differs from typical NAD+ supplements by maintaining controlled NAD+ homeostasis without dangerous side effects, avoiding risks like cancer associated with unregulated NAD+ boosting.
- This research marks a potential shift from focusing solely on prevention or slowing progression to exploring recovery and reversal of Alzheimer's symptoms, with plans underway for human clinical
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