Rare brain fungus with 70% fatality rate rising in healthy patients
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Rare brain fungus with 70% fatality rate rising in healthy patients

Fox News • • health

Key Points:

  • The rare fungal infection Cladophialophora bantiana, which can infect the brain and affects healthy individuals, has seen a near quadrupling of cases in the U.S. between 2023 and 2025, according to CDC data.
  • From 2009 to 2026, 48 confirmed cases were identified across 21 states and D.C., with a median patient age of 68, and about half of infections occurring in people without weakened immune systems.
  • The fungus likely enters the body through inhalation or skin wounds and primarily infects brain tissue, causing severe infections with a 60-70% fatality rate despite aggressive treatment.
  • The increase in cases is not attributed to more testing, as detection rates per brain tissue specimen rose significantly, prompting calls for national tracking and better reporting mechanisms.
  • Early diagnosis is difficult due to the fungus typically causing brain abscesses without external symptoms, and experts urge clinicians to consider C. bantiana in patients showing brain abscess signs.

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