Top Week 1 Start 'Em, Sit 'Em Matchup Plays and Sleepers for Opening Games

Key Points:

• Fantasy managers should prioritize established stars like Ja'Marr Chase, Jahmyr Gibbs, and Brock Bowers in Week 1 lineups, while carefully assessing mid-level options based on matchups and projected roles from last year's data and current depth charts.
• Chargers running back Omarion Hampton is a promising Week 1 pick due to a likely increased workload against the Arizona Cardinals' weak run defense, which ranked 24th in yards per carry allowed last season.
• Seahawks rookie running back Jadarian Price faces a tough matchup against the Patriots' strong rush defense, making it advisable for managers to wait before starting him, especially with Kenneth Walker III now in Kansas City and other backfield uncertainties.
• Raiders wide receiver Tre Tucker is a strong flex option in Week 1, benefiting from a favorable matchup against the Miami Dolphins' struggling defense and increased passing opportunities with new quarterback Kirk Cousins.
• Buffalo Bills' new wideout D.J. Moore may see limited production in Week 1 against the top-ranked Houston Texans defense, likely facing tight coverage from cornerback Derek Stingley Jr., with quarterback Josh Allen expected to favor more familiar targets early in the season.