Week 1 early odds

Week 1 early odds

CBS Sports sports

Key Points:

  • The 2026 NFL regular season kicks off with a Super Bowl LX rematch between the Patriots and Seahawks in Seattle, followed by an international game in Australia featuring the 49ers and Rams at Melbourne Cricket Ground.
  • Week 1 is historically unpredictable for betting, exemplified by last season’s opener where the Raiders upset the Patriots, despite New England reaching the Super Bowl and Las Vegas finishing with the worst record.
  • Key matchups include the Seahawks missing key players like Kenneth Walker III, the 49ers adjusting to a long international trip, and the Browns starting Deshaun Watson against the strong-at-home Jaguars.
  • Several teams debut new coaches and quarterbacks, such as the Dolphins (Jeff Hafley, Malik Willis), Raiders (Klint Kubiak, Kirk Cousins), Vikings (Kyler Murray), and Steelers (Mike McCarthy), adding further uncertainty to early-season betting lines.
  • Notable spreads and trends to watch: Chargers favored by 10.5 points over Cardinals, Eagles favored by 5.5 over Commanders amid offensive changes, and the Packers facing challenges with key players sidelined against the Vikings.

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