What to know about cychlorphine, a new synthetic opioid raising alarm
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What to know about cychlorphine, a new synthetic opioid raising alarm

WRAL • • health

Key Points:

  • The South Carolina Attorney General is warning the public about a new synthetic opioid called cychlorphine, which is more potent and addictive than fentanyl and difficult to detect with standard test strips.
  • Cychlorphine, structurally different from other opioids, can cause severe symptoms including behavioral changes, sleepiness, respiratory failure, and heart attacks.
  • Since 2025, there have been 55 deaths linked to cychlorphine, mainly in the South and Midwest, with high occurrences in Ohio, Tennessee, and Texas.
  • The drug is often manufactured overseas and smuggled into the U.S. by drug cartels, who prioritize profit over human lives, according to South Carolina Attorney General Alan Wilson.
  • Medical experts in Conway, South Carolina, have not yet seen overdoses but expect the drug to appear locally soon due to the growing prevalence of fentanyl derivatives nationwide.

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